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Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model
Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, has been implicated in the onset and development of the ocular complications of diabetes, including cataracts and retinopathy. Despite decades of research conducted to address possible mechanisms, questions still persis...
Autores principales: | Petrash, Jonathan Mark, Shieh, Biehuoy, Ammar, David A., Pedler, Michelle G., Orlicky, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305400/ https://www.ncbi.nlm.nih.gov/pubmed/34357344 http://dx.doi.org/10.3390/metabo11070450 |
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