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Genomic Mosaicism Formed by Somatic Variation in the Aging and Diseased Brain
Over the past 20 years, analyses of single brain cell genomes have revealed that the brain is composed of cells with myriad distinct genomes: the brain is a genomic mosaic, generated by a host of DNA sequence-altering processes that occur somatically and do not affect the germline. As such, these se...
Autores principales: | Costantino, Isabel, Nicodemus, Juliet, Chun, Jerold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305509/ https://www.ncbi.nlm.nih.gov/pubmed/34356087 http://dx.doi.org/10.3390/genes12071071 |
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