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Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia

Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a t...

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Autores principales: Alefishat, Eman, Jarab, Anan S., Al-Qerem, Walid, Abu-Zaytoun, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305629/
https://www.ncbi.nlm.nih.gov/pubmed/34203226
http://dx.doi.org/10.3390/healthcare9070813
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author Alefishat, Eman
Jarab, Anan S.
Al-Qerem, Walid
Abu-Zaytoun, Lina
author_facet Alefishat, Eman
Jarab, Anan S.
Al-Qerem, Walid
Abu-Zaytoun, Lina
author_sort Alefishat, Eman
collection PubMed
description Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a total of 228 dyslipidemia patients. The Beliefs about Medicines Questionnaire was also used to assess patients’ beliefs about medications. The majority of the current study participants (73.2%) reported non-adherence to the prescribed medications. There were significant negative associations between medication adherence and concerns of prescription drug use (B = −0.41, p-value < 0.01), duration of dyslipidemia (B = −0.22, p-value < 0.01), and the number of medications (B = −0.64, p-value < 0.01). Positive associations were found between medication adherence and the necessity of prescription drug use (B = 0.43, p-value < 0.01), taking statin and fibrate (B = 2.04, p-value < 0.01), and moderate-intensity statin (B = 2.34, p-value < 0.01). As for patients’ beliefs about medications, the item “My medicine to lower my cholesterol disrupted my life” had the highest mean (3.50 ± 0.99). This study revealed a low adherence rate to medication among patients with dyslipidemia. It also demonstrates modifiable factors such as beliefs regarding perceived risk, medication harms, treatment duration, and the number of medications associated with poor adherence in patients with dyslipidemia.
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spelling pubmed-83056292021-07-25 Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia Alefishat, Eman Jarab, Anan S. Al-Qerem, Walid Abu-Zaytoun, Lina Healthcare (Basel) Article Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a total of 228 dyslipidemia patients. The Beliefs about Medicines Questionnaire was also used to assess patients’ beliefs about medications. The majority of the current study participants (73.2%) reported non-adherence to the prescribed medications. There were significant negative associations between medication adherence and concerns of prescription drug use (B = −0.41, p-value < 0.01), duration of dyslipidemia (B = −0.22, p-value < 0.01), and the number of medications (B = −0.64, p-value < 0.01). Positive associations were found between medication adherence and the necessity of prescription drug use (B = 0.43, p-value < 0.01), taking statin and fibrate (B = 2.04, p-value < 0.01), and moderate-intensity statin (B = 2.34, p-value < 0.01). As for patients’ beliefs about medications, the item “My medicine to lower my cholesterol disrupted my life” had the highest mean (3.50 ± 0.99). This study revealed a low adherence rate to medication among patients with dyslipidemia. It also demonstrates modifiable factors such as beliefs regarding perceived risk, medication harms, treatment duration, and the number of medications associated with poor adherence in patients with dyslipidemia. MDPI 2021-06-28 /pmc/articles/PMC8305629/ /pubmed/34203226 http://dx.doi.org/10.3390/healthcare9070813 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alefishat, Eman
Jarab, Anan S.
Al-Qerem, Walid
Abu-Zaytoun, Lina
Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_full Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_fullStr Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_full_unstemmed Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_short Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_sort factors associated with medication non-adherence in patients with dyslipidemia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305629/
https://www.ncbi.nlm.nih.gov/pubmed/34203226
http://dx.doi.org/10.3390/healthcare9070813
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