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Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer

Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma (PDAC) cases. No major causative gene defect has yet been identified, but germline mutations in predisposition genes BRCA1/2, CDKN2A and PALB2 c...

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Detalles Bibliográficos
Autores principales:	Slater, Emily P., Wilke, Lisa M., Böhm, Lutz Benedikt, Strauch, Konstantin, Lutz, Manuel, Gercke, Norman, Matthäi, Elvira, Hemminki, Kari, Försti, Asta, Schlesner, Matthias, Paramasivam, Nagarajan, Bartsch, Detlef K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305658/ https://www.ncbi.nlm.nih.gov/pubmed/34357098 http://dx.doi.org/10.3390/jpm11070631

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