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Epigenetic Drifts during Long-Term Intestinal Organoid Culture

Organoids retain the morphological and molecular patterns of their tissue of origin, are self-organizing, relatively simple to handle and accessible to genetic engineering. Thus, they represent an optimal tool for studying the mechanisms of tissue maintenance and aging. Long-term expansion under sta...

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Detalles Bibliográficos
Autores principales: Thalheim, Torsten, Siebert, Susann, Quaas, Marianne, Herberg, Maria, Schweiger, Michal R., Aust, Gabriela, Galle, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305684/
https://www.ncbi.nlm.nih.gov/pubmed/34359888
http://dx.doi.org/10.3390/cells10071718