Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts

Pancreatic ductal adenocarcinoma (PDAC) is associated with poor prognosis. This is attributed to the disease already being advanced at presentation and having a particularly aggressive tumor biology. The PDAC tumor microenvironment (TME) is characterized by a dense desmoplastic stroma, dominated by...

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Detalles Bibliográficos
Autores principales: Pfeifer, Ester, Burchell, Joy M., Dazzi, Francesco, Sarker, Debashis, Beatson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305815/
https://www.ncbi.nlm.nih.gov/pubmed/34359823
http://dx.doi.org/10.3390/cells10071653

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