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Epigenetic reprogramming of cell identity: lessons from development for regenerative medicine
Epigenetic mechanisms are known to define cell-type identity and function. Hence, reprogramming of one cell type into another essentially requires a rewiring of the underlying epigenome. Cellular reprogramming can convert somatic cells to induced pluripotent stem cells (iPSCs) that can be directed t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305869/ https://www.ncbi.nlm.nih.gov/pubmed/34301318 http://dx.doi.org/10.1186/s13148-021-01131-4 |