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Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

BACKGROUND: The ability to achieve high peak viable cell density earlier in CHO cell culture and maintain an extended cell viability throughout the production process is highly desirable to increase recombinant protein yields, reduce host cell impurities for downstream processing and reduce the cost...

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Detalles Bibliográficos
Autores principales:	Bryan, Laura, Henry, Michael, Kelly, Ronan M., Frye, Christopher C., Osborne, Matthew D., Clynes, Martin, Meleady, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305936/ https://www.ncbi.nlm.nih.gov/pubmed/34301236 http://dx.doi.org/10.1186/s12896-021-00704-8

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