Cargando…

In Vitro Antiplatelet Activity of Mulberroside C through the Up-Regulation of Cyclic Nucleotide Signaling Pathways and Down-Regulation of Phosphoproteins

Physiological agonists trigger signaling cascades, called “inside-out signaling”, and activated platelets facilitate adhesion, shape change, granule release, and structural change of glycoprotein IIb/IIIa (αIIb/β3). Activated αIIb/β3 interacts with fibrinogen and begins second signaling cascades cal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Hyuk-Woo, Lee, Dong-Ha, Rhee, Man Hee, Shin, Jung-Hae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305937/ https://www.ncbi.nlm.nih.gov/pubmed/34209363 http://dx.doi.org/10.3390/genes12071024

Ejemplares similares

Vasodilator-stimulated phosphoprotein-phosphorylation by ginsenoside Ro inhibits fibrinogen binding to αIIb/β(3) in thrombin-induced human platelets
por: Shin, Jung-Hae, et al.
Publicado: (2016)

Mulberroside A from Cortex Mori Enhanced Gut Integrity in Diabetes
por: Xu, Yinyan, et al.
Publicado: (2021)

Anti-Thrombotic Effects of Artesunate through Regulation of cAMP and PI3K/MAPK Pathway on Human Platelets
por: Yoon, Shin-Sook, et al.
Publicado: (2022)

Variations in the Levels of Mulberroside A, Oxyresveratrol, and Resveratrol in Mulberries in Different Seasons and during Growth
por: Zhou, Jin, et al.
Publicado: (2013)

Fluorophore‐Labeled Cyclic Nucleotides as Potent Agonists of Cyclic Nucleotide‐Regulated Ion Channels
por: Lelle, Marco, et al.
Publicado: (2020)

Mulberroside F from In Vitro Culture of Mulberry and the Potential Use of the Root Extracts in Cosmeceutical Applications
por: Thamrongwatwongsa, Jiralapat, et al.
Publicado: (2022)

Inhibitory effects of total saponin from Korean Red Ginseng on [Ca(2+)](i) mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets
por: Shin, Jung-Hae, et al.
Publicado: (2015)

An Efficient Preparation of Mulberroside A from the Branch Bark of Mulberry and Its Effect on the Inhibition of Tyrosinase Activity
por: Wang, Shu, et al.
Publicado: (2014)

Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms
por: Jayakumar, Thanasekaran, et al.
Publicado: (2017)

Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms
por: Jayakumar, Thanasekaran, et al.
Publicado: (2020)

The Inhibitory Effects of Protaetia brevitarsis seulensis Larvae Extract on Human Platelet Aggregation and Glycoprotein IIb/IIIa Expression
por: Kwon, Hyuk-Woo, et al.
Publicado: (2023)

Antiplatelet and Antithrombotic Effects of Epimedium koreanum Nakai
por: Irfan, Muhammad, et al.
Publicado: (2021)

Calcium and cyclic nucleotide regulation in incubated mouse retinas
Publicado: (1978)

Retinal Cyclic Nucleotide-Gated Channel Regulation by Calmodulin
por: Bej, Aritra, et al.
Publicado: (2022)

Ginsenoside Rk1 suppresses platelet mediated thrombus formation by downregulation of granule release and α(IIb)β(3) activation
por: Shin, Jung-Hae, et al.
Publicado: (2021)

Mulberroside A ameliorates CCl4‐induced liver fibrosis in mice via inhibiting pro‐inflammatory response
por: Shi, Baozhang, et al.
Publicado: (2023)

Vimentin: a phosphoprotein under hormonal regulation
Publicado: (1981)

Phosphoproteins regulated by heat stress in rice leaves
por: Chen, Xinhai, et al.
Publicado: (2011)

Derrone Inhibits Platelet Aggregation, Granule Secretion, Thromboxane A(2) Generation, and Clot Retraction: An In Vitro Study
por: Shin, Jung-Hae, et al.
Publicado: (2021)

Cyclic nucleotide regulation of the contractile proteins in mammalian cardiac muscle
Publicado: (1980)

Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation
por: Brocke, Stefan, et al.
Publicado: (2022)

Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases
por: Gambaryan, Stepan, et al.
Publicado: (2023)

Ulmus parvifolia Modulates Platelet Functions and Inhibits Thrombus Formation by Regulating Integrin α(IIb)β(3) and cAMP Signaling
por: Irfan, Muhammad, et al.
Publicado: (2020)

Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1
por: Kwon, Sora, et al.
Publicado: (2016)

Inhibitory effects of thromboxane A(2) generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A(2) phosphorylation and arachidonic acid release
por: Shin, Jung-Hae, et al.
Publicado: (2019)

Pharmacological Actions of 5-Hydroxyindolin-2 on Modulation of Platelet Functions and Thrombus Formation via Thromboxane A(2) Inhibition and cAMP Production
por: Kwon, Hyuk-Woo, et al.
Publicado: (2022)

Cyclic nucleotide regulation of teleost rod photoreceptor inner segment length
Publicado: (1993)

Cellular signaling mediated by nitrated cyclic nucleotide and regulated by hydrogen sulfide
por: Akaike, Takaaki
Publicado: (2011)

Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets
por: Heimann, Emilia, et al.
Publicado: (2010)

Determinants of ligand selectivity in a cyclic nucleotide–regulated potassium channel
por: Pessoa, João, et al.
Publicado: (2014)

Quantitative iTRAQ-based proteomic analysis of phosphoproteins and ABA-regulated phosphoproteins in maize leaves under osmotic stress
por: Hu, Xiuli, et al.
Publicado: (2015)

Importance of the αC-helix in the cyclic nucleotide binding domain for the stable channel regulation and function of cyclic nucleotide gated ion channels in Arabidopsis
por: Chin, Kimberley, et al.
Publicado: (2010)

Hormonally regulated phosphoprotein of turkey erythrocytes: localization to plasma membrane
Publicado: (1979)

Golgi Phosphoprotein 3 Regulates the Physical Association of Glycolipid Glycosyltransferases †
por: Ruggiero, Fernando M., et al.
Publicado: (2022)

Cyclic decomposition explains a photosynthetic down regulation for Chlamydomonas reinhardtii
por: Chapman, Stephen P., et al.
Publicado: (2017)

A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains
por: Kornev, Alexandr P., et al.
Publicado: (2008)

Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation
por: Lee, Ye-Ming, et al.
Publicado: (2010)

Structure and Energetics of Allosteric Regulation of HCN2 Ion Channels by Cyclic Nucleotides
por: DeBerg, Hannah A., et al.
Publicado: (2016)

Vasodilator-stimulated phosphoprotein (VASP) is not a major mediator of platelet aggregation, thrombogenesis, haemostasis, and antiplatelet effect of prasugrel in rats
por: Ito, Yusuke, et al.
Publicado: (2018)

Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin
por: Woo, Seon Min, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mn299lsgo6dgthq9jb54d6rbpm