Synthesis and Antiproliferative Activity of Phosphorus Substituted 4-Cyanooxazolines, 2-Aminocyanooxazolines, 2-Iminocyanooxazolidines and 2-Aminocyanothiazolines by Rearrangement of Cyanoaziridines

Several phosphorus-substituted N-acylated cyanoaziridines 2 and N-carbamoylated cyanoziridines 5 were prepared in good to high yields. N-Acylated cyanoaziridines 2 were used, after ring expansion, in an efficient synthesis of oxazoline derivative 3a and in a completely regio-controlled reaction in t...

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Detalles Bibliográficos
Autores principales: Carramiñana, Victor, Ochoa de Retana, Ana M., Palacios, Francisco, de los Santos, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305992/
https://www.ncbi.nlm.nih.gov/pubmed/34299540
http://dx.doi.org/10.3390/molecules26144265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305992/
https://www.ncbi.nlm.nih.gov/pubmed/34299540
http://dx.doi.org/10.3390/molecules26144265

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