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Therapeutic Cancer Vaccination with Immunopeptidomics-Discovered Antigens Confers Protective Antitumor Efficacy

SIMPLE SUMMARY: Immunotherapy has revolutionized cancer treatment, yet many tumors remain resistant to current immuno-oncology therapies. Here we explore a novel, customized oncolytic adenovirus vaccine platform as immunotherapy in a resistant tumor model. We present a workflow for customizing the o...

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Detalles Bibliográficos
Autores principales: Peltonen, Karita, Feola, Sara, Umer, Husen M., Chiaro, Jacopo, Mermelekas, Georgios, Ylösmäki, Erkko, Pesonen, Sari, Branca, Rui M. M., Lehtiö, Janne, Cerullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306067/
https://www.ncbi.nlm.nih.gov/pubmed/34298622
http://dx.doi.org/10.3390/cancers13143408