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Linking Fibrotic Remodeling and Ultrastructural Alterations of Alveolar Epithelial Cells after Deletion of Nedd4-2

Our previous study showed that in adult mice, conditional Nedd4-2-deficiency in club and alveolar epithelial type II (AE2) cells results in impaired mucociliary clearance, accumulation of Muc5b and progressive, terminal pulmonary fibrosis within 16 weeks. In the present study, we investigated ultras...

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Detalles Bibliográficos
Autores principales:	Engelmann, Theresa A., Knudsen, Lars, Leitz, Dominik H. W., Duerr, Julia, Beers, Michael F., Mall, Marcus A., Ochs, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306112/ https://www.ncbi.nlm.nih.gov/pubmed/34299227 http://dx.doi.org/10.3390/ijms22147607

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