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Regulation of Mitochondrial Respiration by VDAC Is Enhanced by Membrane-Bound Inhibitors with Disordered Polyanionic C-Terminal Domains

The voltage-dependent anion channel (VDAC) is the primary regulating pathway of water-soluble metabolites and ions across the mitochondrial outer membrane. When reconstituted into lipid membranes, VDAC responds to sufficiently large transmembrane potentials by transitioning to gated states in which...

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Detalles Bibliográficos
Autores principales:	Rostovtseva, Tatiana K., Bezrukov, Sergey M., Hoogerheide, David P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306229/ https://www.ncbi.nlm.nih.gov/pubmed/34298976 http://dx.doi.org/10.3390/ijms22147358

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