RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells

The regulator of G-protein signaling 5 (RGS5) acts as an inhibitor of Gα(q/11) and Gα(i/o) activity in vascular smooth muscle cells (VSMCs), which regulate arterial tone and blood pressure. While RGS5 has been described as a crucial determinant regulating the VSMC responses during various vascular r...

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Detalles Bibliográficos
Autores principales: Demirel, Eda, Arnold, Caroline, Garg, Jaspal, Jäger, Marius Andreas, Sticht, Carsten, Li, Rui, Kuk, Hanna, Wettschureck, Nina, Hecker, Markus, Korff, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306326/
https://www.ncbi.nlm.nih.gov/pubmed/34359918
http://dx.doi.org/10.3390/cells10071748

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