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Intrabronchial application of extracellular histones shows no proinflammatory effects in swine in a translational pilot study
OBJECTIVE: Extracellular histones have been identified as one molecular factor that can cause and sustain alveolar damage and were linked to high mortality rates in critically ill patients. In this pilot study, we wanted to validate the proinflammatory in vivo effects of local histone application in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306385/ https://www.ncbi.nlm.nih.gov/pubmed/34301315 http://dx.doi.org/10.1186/s13104-021-05704-7 |