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Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines

Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides. Some lipoproteins and lipopolysaccharides are pyrogens; thus, GMMA-based vaccines are intr...

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Detalles Bibliográficos
Autores principales:	Carson, Danielle, Myhill, Sophie, Palmieri, Elena, Necchi, Francesca, Rijpkema, Sjoerd, Micoli, Francesca, Nordgren, Ida Karin, Rossi, Omar, Vipond, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306433/ https://www.ncbi.nlm.nih.gov/pubmed/34202832 http://dx.doi.org/10.3390/microorganisms9071375

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