Cargando…
KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
SIMPLE SUMMARY: Glioblastoma (GB) is the most aggressive brain tumor characterized by necrosis, excessive proliferation, and invasiveness. Despite relevant progress in conventional treatments, the survival rate for patients with GB remains low. The present study investigated the potential effect of...
Autores principales: | Scuderi, Sarah Adriana, Casili, Giovanna, Ardizzone, Alessio, Forte, Stefano, Colarossi, Lorenzo, Sava, Serena, Paterniti, Irene, Esposito, Emanuela, Cuzzocrea, Salvatore, Campolo, Michela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306782/ https://www.ncbi.nlm.nih.gov/pubmed/34298658 http://dx.doi.org/10.3390/cancers13143444 |
Ejemplares similares
-
Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021) -
Inhibition of Prolyl Oligopeptidase Prevents Consequences of Reperfusion following Intestinal Ischemia
por: Filippone, Alessia, et al.
Publicado: (2021) -
The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance
por: Toppila, Maija, et al.
Publicado: (2023) -
The Protective Role of Prolyl Oligopeptidase (POP) Inhibition in Kidney Injury Induced by Renal Ischemia–Reperfusion
por: Casili, Giovanna, et al.
Publicado: (2021) -
The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model
por: Casili, Giovanna, et al.
Publicado: (2020)