A New N-Substituted 1H-Isoindole-1,3(2H)-Dione Derivative—Synthesis, Structure and Affinity for Cyclooxygenase Based on In Vitro Studies and Molecular Docking

Isoindoline-1,3-dione derivatives constitute an important group of medicinal substances. In this study, nine new 1H-isoindole-1,3(2H)-dione derivatives and five potential pharmacophores were obtained in good yield (47.24–92.91%). The structure of the new imides was confirmed by the methods of elemen...

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Detalles Bibliográficos
Autores principales: Szkatuła, Dominika, Krzyżak, Edward, Stanowska, Paulina, Duda, Magdalena, Wiatrak, Benita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306876/
https://www.ncbi.nlm.nih.gov/pubmed/34299298
http://dx.doi.org/10.3390/ijms22147678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306876/
https://www.ncbi.nlm.nih.gov/pubmed/34299298
http://dx.doi.org/10.3390/ijms22147678

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