Cargando…

Repurposing DPP-4 Inhibitors for Colorectal Cancer: A Retrospective and Single Center Study

SIMPLE SUMMARY: Colorectal cancer is one of the most common causes and the leading cause of cancer deaths worldwide. Its poor prognosis highlights the urgent need for more effective treatments. Repurposing approved drugs is a promising strategy as preclinical screenings can be minimized. The aim of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ng, Lui, Foo, Dominic Chi-Chung, Wong, Carlos King-Ho, Man, Abraham Tak-Ka, Lo, Oswens Siu-Hung, Law, Wai-Lun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306906/ https://www.ncbi.nlm.nih.gov/pubmed/34298800 http://dx.doi.org/10.3390/cancers13143588

Ejemplares similares

High Expression of a Cancer Stemness-Related Gene, Chromobox 8 (CBX8), in Normal Tissue Adjacent to the Tumor (NAT) Is Associated with Poor Prognosis of Colorectal Cancer Patients
por: Ng, Lui, et al.
Publicado: (2022)

Serum microRNA Levels as a Biomarker for Diagnosing Non-Alcoholic Fatty Liver Disease in Chinese Colorectal Polyp Patients
por: Ng, Lui, et al.
Publicado: (2023)

CD26 Induces Colorectal Cancer Angiogenesis and Metastasis through CAV1/MMP1 Signaling
por: Ng, Lui, et al.
Publicado: (2022)

High Levels of Tumor miR-187-3p—A Potential Tumor-Suppressor microRNA—Are Correlated with Poor Prognosis in Colorectal Cancer
por: Ng, Lui, et al.
Publicado: (2022)

A Pilot Study Investigating the Expression Levels of Pluripotency-Associated Genes in Rectal Swab Samples for Colorectal Polyp and Cancer Diagnosis and Prognosis
por: Sin, Ryan Wai-Yan, et al.
Publicado: (2021)

Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center
por: Chan, Toi Yin, et al.
Publicado: (2019)

Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer
por: Lam, Colin Siu-Chi, et al.
Publicado: (2017)

Small RNA Profiling of piRNAs in Colorectal Cancer Identifies Consistent Overexpression of piR-24000 That Correlates Clinically with an Aggressive Disease Phenotype
por: Iyer, Deepak Narayanan, et al.
Publicado: (2020)

The Clinicopathological Significance of miR-133a in Colorectal Cancer
por: Wan, Timothy Ming-Hun, et al.
Publicado: (2014)

MiR-509-3p is oncogenic, targets the tumor suppressor PHLPP2, and functions as a novel tumor adjacent normal tissue based prognostic biomarker in colorectal cancer
por: Iyer, Deepak Narayanan, et al.
Publicado: (2022)

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer
por: Ng, Lui, et al.
Publicado: (2017)

Rare complication of inflammatory bowel disease-like colitis from glycogen storage disease type 1b and its surgical management: A case report
por: Lui, Frederick Chi-Wai, et al.
Publicado: (2021)

Post-Operative Plasma Osteopontin Predicts Distant Metastasis in Human Colorectal Cancer
por: Ng, Lui, et al.
Publicado: (2015)

Prognostic Significance of CD26 in Patients with Colorectal Cancer
por: Lam, Colin Siu-Chi, et al.
Publicado: (2014)

Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer
por: Ng, Lui, et al.
Publicado: (2015)

Survival following laparoscopic versus open resection for colorectal cancer
por: Law, Wai Lun, et al.
Publicado: (2012)

Surgical management and outcome of rectal carcinoids in a university hospital
por: Wei, Rockson, et al.
Publicado: (2015)

A rare case of rectal prolapse after Deloyers procedure in a patient with Hirschsprung’s disease: A case report
por: Law, Brandon Cheuk-Fung, et al.
Publicado: (2019)

How does lymph node yield affect survival outcomes of stage I and II colon cancer?
por: Foo, Chi Chung, et al.
Publicado: (2020)

Rates of metachronous adenoma after curative resection for left-sided or right-sided colon cancer
por: Lam, Yuk Fai, et al.
Publicado: (2018)

Melanosis coli: Harmless pigmentation? A case-control retrospective study of 657 cases
por: Liu, Zhong Hui, et al.
Publicado: (2017)

Emergence of CD26+ Cancer Stem Cells with Metastatic Properties in Colorectal Carcinogenesis
por: Cheung, Alvin Ho-Kwan, et al.
Publicado: (2017)

Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer
por: Kerkhove, Lisa, et al.
Publicado: (2023)

Enhanced recovery program in laparoscopic colectomy for cancer
por: Poon, Jensen T. C., et al.
Publicado: (2010)

Laparoscopic colorectal resections with and without routine mechanical bowel preparation: A comparative study
por: Chan, Miu Yee, et al.
Publicado: (2016)

Urinary Polyamines: A Pilot Study on Their Roles as Prostate Cancer Detection Biomarkers
por: Tsoi, Tik-Hung, et al.
Publicado: (2016)

Potential repurposing of DPP4 inhibitors for target therapy resistance in renal cell carcinoma
por: Horie, Kuniko, et al.
Publicado: (2023)

Impact of neoadjuvant treatment on total mesorectal excision for ultra-low rectal cancers
por: Lim, Yon Kuei, et al.
Publicado: (2010)

The current management of acute uncomplicated appendicitis: should there be a change in paradigm? A systematic review of the literatures and analysis of treatment performance
por: Poon, Samuel Ho Ting, et al.
Publicado: (2017)

Robotic anterior resection in a patient with situs inversus: is it merely a mirror image of everything?
por: Foo, Chi Chung, et al.
Publicado: (2014)

Editorial: Evolving roles of piRNAs in solid tumors
por: Ng, Lui, et al.
Publicado: (2023)

Simultaneous transurethral bipolar enucleation of the prostate, supine ultrasound-guided percutaneous nephrolithotomy and open cystolithotomy: A feasible and safe approach
por: Lo, Ka Lun, et al.
Publicado: (2020)

Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway
por: Pan, Yi, et al.
Publicado: (2018)

Transanal Total Mesorectal Excision With Single-Incision Laparoscopy for Rectal Cancer
por: Foo, Dominic Chi-chung, et al.
Publicado: (2016)

Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study
por: Chittepu, Veera C. S. R., et al.
Publicado: (2019)

In search of the optimal management strategy for non‐alcoholic fatty liver disease in type 2 diabetes patients
por: Lee, Chi‐Ho, et al.
Publicado: (2020)

Letter to the Editor: ‘Euthyroid sick syndrome as an early surrogate marker of poor outcome in mild SARS‑CoV‑2 disease’—prognostic significance of non-thyroidal illness syndrome across the whole spectrum of COVID-19 severity
por: Lui, David Tak Wai, et al.
Publicado: (2022)

Synthesis of a Conformationally Stable Atropisomeric Pair of Biphenyl Scaffold Containing Additional Stereogenic Centers
por: Yeung, Chi-Tung, et al.
Publicado: (2019)

Health-related quality of life and risk of colorectal cancer recurrence and All-cause death among advanced stages of colorectal cancer 1-year after diagnosis
por: Wong, Carlos KH, et al.
Publicado: (2014)

Development and pilot evaluation of a mobile app on parent-child exercises to improve physical activity and psychosocial outcomes of Hong Kong Chinese children
por: Wong, Rosa Sze Man, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2409p8m68eoh443hova6f8opri