Cargando…

Novel Mutations in X-Linked, USP26-Induced Asthenoteratozoospermia and Male Infertility

Male infertility is a multifactorial disease with a strong genetic background. Abnormal sperm morphologies have been found to be closely related to male infertility. Here, we conducted whole-exome sequencing in a cohort of 150 Han Chinese men with asthenoteratozoospermia. Two novel hemizygous mutati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chunyu, Shen, Ying, Shen, Qunshan, Zhang, Wen, Wang, Jiaxiong, Tang, Shuyan, Wu, Huan, Tian, Shixiong, Cong, Jiangshan, He, Xiaojin, Jin, Li, Zhang, Feng, Jiang, Xiaohui, Cao, Yunxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307012/ https://www.ncbi.nlm.nih.gov/pubmed/34202084 http://dx.doi.org/10.3390/cells10071594

Ejemplares similares

Deficiency of X-linked TENT5D causes male infertility by disrupting the mRNA stability during spermatogenesis
por: Cong, Jiangshan, et al.
Publicado: (2022)

A novel frameshift mutation in DNAH6 associated with male infertility and asthenoteratozoospermia
por: Huang, Fei, et al.
Publicado: (2023)

Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
por: Xu, Chuan, et al.
Publicado: (2022)

Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans
por: Lv, Mingrong, et al.
Publicado: (2023)

Correction to: Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF
por: Xu, Chuan, et al.
Publicado: (2022)

Novel homozygous variants in TTC12 cause male infertility with asthenoteratozoospermia owing to dynein arm complex and mitochondrial sheath defects in flagella
por: Meng, Lanlan, et al.
Publicado: (2023)

Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations
por: Lv, Mingrong, et al.
Publicado: (2022)

The association between mutations in ubiquitin-specific protease 26 (USP26) and male infertility: a systematic review and meta-analysis
por: Li, Qin-Yu, et al.
Publicado: (2022)

Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermia
por: Tang, Dongdong, et al.
Publicado: (2022)

Novel variants in helicase for meiosis 1 lead to male infertility due to non-obstructive azoospermia
por: Tang, Dongdong, et al.
Publicado: (2021)

Correction: Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermia
por: Tang, Dongdong, et al.
Publicado: (2022)

Case Report: Novel Biallelic Mutations in ARMC4 Cause Primary Ciliary Dyskinesia and Male Infertility in a Chinese Family
por: Gao, Yang, et al.
Publicado: (2021)

Homozygous mutation in DNALI1 leads to asthenoteratozoospermia by affecting the inner dynein arms
por: Sha, Yanwei, et al.
Publicado: (2023)

A recurrent homozygous missense mutation in CCDC103 causes asthenoteratozoospermia due to disorganized dynein arms
por: Zubair, Muhammad, et al.
Publicado: (2022)

Correlation of Novel Single Nucleotide Polymorphisms of USP26, TEX15 and TNP2 Genes with Male Infertility in North West of Iran
por: Ghadirkhomi, Elham, et al.
Publicado: (2022)

Loss of DRC1 function leads to multiple morphological abnormalities of the sperm flagella and male infertility in human and mouse
por: Zhang, Jintao, et al.
Publicado: (2021)

AB26. Y chromosome and male infertility
por: Iijima, Masashi
Publicado: (2014)

Editorial: Genetic factors in male infertility
por: He, Xiaojin, et al.
Publicado: (2023)

Effect of Phosphodiesterase-5 Inhibitors on the Treatment of Male Infertility: A Systematic Review and Meta-Analysis
por: Dong, Liang, et al.
Publicado: (2021)

Mechanisms linking obesity to male infertility
por: Katib, Atif
Publicado: (2015)

Novel HYDIN variants associated with male infertility in two Chinese families
por: Yu, Hui, et al.
Publicado: (2023)

Retrospective Study to Compare Frozen-Thawed Embryo Transfer with Fresh Embryo Transfer on Pregnancy Outcome Following Intracytoplasmic Sperm Injection for Male Infertility
por: Wang, Xue, et al.
Publicado: (2018)

Effect of phosphodiesterase-5 inhibitors (PDE5is) on the treatment of male infertility: A protocol for systematic review and meta-analysis
por: Dong, Liang, et al.
Publicado: (2019)

Impact of the COVID-19 Pandemic on Partner Relationships and Sexual and Reproductive Health: Cross-Sectional, Online Survey Study
por: Li, Guanjian, et al.
Publicado: (2020)

Diet Quality Scores and Asthenoteratozoospermia Risk: Finding From a Hospital-Based Case–Control Study in China
por: Cui, Qi, et al.
Publicado: (2022)

Increased Gonadotropins and prolactin are linked to infertility in males
por: Gangwar, Pravin Kumar, et al.
Publicado: (2020)

The Effect of N-Acetyl-Cysteine on NRF2 Antioxidant Gene Expression in Asthenoteratozoospermia Men: A Clinical Trial Study
por: Jannatifar, Rahil, et al.
Publicado: (2020)

Ubiquitin Specific Protease 26 (USP26) Expression Analysis in Human Testicular and Extragonadal Tissues Indicates Diverse Action of USP26 in Cell Differentiation and Tumorigenesis
por: Wosnitzer, Matthew S., et al.
Publicado: (2014)

Identification of Novel Biallelic TLE6 Variants in Female Infertility With Preimplantation Embryonic Lethality
por: Zhang, Manyu, et al.
Publicado: (2021)

The osteoprotective role of USP26 in coordinating bone formation and resorption
por: Li, Changwei, et al.
Publicado: (2022)

Retrospective Analysis of the First Collection versus the Second Collection in Severe Oligo-asthenoteratozoospermia Cases in Self-Intracytoplasmic Sperm Injection Patients
por: Patel, Deven V., et al.
Publicado: (2022)

MicroRNA-26b inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting USP9X
por: Shen, Gang, et al.
Publicado: (2014)

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
por: Typas, Dimitris, et al.
Publicado: (2015)

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
por: Typas, Dimitris, et al.
Publicado: (2016)

Microbiology and immune mechanisms associated with male infertility
por: Chen, Jin, et al.
Publicado: (2023)

DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath
por: Wu, Huan, et al.
Publicado: (2023)

Computationally predicted pathogenic USP9X mutation identified in infertile men does not affect spermatogenesis in mice
por: Liu, Wei, et al.
Publicado: (2022)

Identification of biallelic variations of CEP70 in patients with male infertility
por: Ruan, Tiechao, et al.
Publicado: (2023)

USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ
por: Tang, Jianing, et al.
Publicado: (2022)

Effect of oral alpha-lipoic acid (ALA) on the treatment of male infertility: A protocol for systematic review and meta-analysis
por: Dong, Liang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qoqucr1ikv3h43ccd186pikevg