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Tbx21 and Foxp3 Are Epigenetically Stabilized in T-Bet(+) Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs

During influenza A virus (IAV) infections, CD4(+) T cell responses within infected lungs mainly involve T helper 1 (Th1) and regulatory T cells (Tregs). Th1-mediated responses favor the co-expression of T-box transcription factor 21 (T-bet) in Foxp3(+) Tregs, enabling the efficient Treg control of T...

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Detalles Bibliográficos
Autores principales:	Elfaki, Yassin, Yang, Juhao, Boehme, Julia, Schultz, Kristin, Bruder, Dunja, Falk, Christine S., Huehn, Jochen, Floess, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307036/ https://www.ncbi.nlm.nih.gov/pubmed/34299148 http://dx.doi.org/10.3390/ijms22147522

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