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VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux

SIMPLE SUMMARY: Cellular adhesion plays an important role in the development of resistance to chemotherapy (chemoresistance) that represents a major hurdle in the treatment of leukemia and which is a major cause for patient relapse. In this study, we evaluated if cell adhesion to the molecule VCAM-1...

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Detalles Bibliográficos
Autores principales: Berrazouane, Sofiane, Doucet, Alexie, Boisvert, Marc, Barabé, Frédéric, Aoudjit, Fawzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307050/
https://www.ncbi.nlm.nih.gov/pubmed/34298726
http://dx.doi.org/10.3390/cancers13143512