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Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation
Background: The aim of this study was to determine whether the presence of disproportionate vertebral bodies is a risk factor for disc herniation (DH). Methods: Sixty-seven consecutive patients (m: 31 f: 36) who underwent lumbar discectomy for symptomatic DH at one level between L3 and S1 were retro...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307056/ https://www.ncbi.nlm.nih.gov/pubmed/34300340 http://dx.doi.org/10.3390/jcm10143174 |
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author | Läubli, Ralph Brugger, Robin Pirvu, Tatiana Hoppe, Sven Sieroń, Dominik Szyluk, Karol Albers, Christoph E. Christe, Andreas |
author_facet | Läubli, Ralph Brugger, Robin Pirvu, Tatiana Hoppe, Sven Sieroń, Dominik Szyluk, Karol Albers, Christoph E. Christe, Andreas |
author_sort | Läubli, Ralph |
collection | PubMed |
description | Background: The aim of this study was to determine whether the presence of disproportionate vertebral bodies is a risk factor for disc herniation (DH). Methods: Sixty-seven consecutive patients (m: 31 f: 36) who underwent lumbar discectomy for symptomatic DH at one level between L3 and S1 were retrospectively included. The last three motion segments (3 × 67 = 201) were assessed on sagittal MRI scans. A disproportionate motion segment was defined as the difference of more than 10% of the antero-posterior diameter of two adjacent endplates. Results: DH was present in 6/67 (9%), 26/67 (38.8%), and 35/67 (52.2%) patients at L3/4, L4/5, and L5/S1, respectively. A total of 14 of 67 patients demonstrated a disproportionate motion segment at the discectomy level (20.9%). A total of 23 of the 201 (11.4%) investigated motion segments met our criteria for a disproportionate motion segment. In our study population, when one of the 201 segments was disproportionate, the positive predictive value (PPV) for DH increased toward the lower segments: the PPV at the L5/S1 level was 83.0%. The odds ratio of disproportion for DH was the highest at the L5/S1 level, with 6.0 ± 0.82 (p = 0.017). Conclusions: The presence of a disproportionate motion segment in the lower spine may lead to a significant higher risk for DH in patients undergoing discectomy. |
format | Online Article Text |
id | pubmed-8307056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83070562021-07-25 Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation Läubli, Ralph Brugger, Robin Pirvu, Tatiana Hoppe, Sven Sieroń, Dominik Szyluk, Karol Albers, Christoph E. Christe, Andreas J Clin Med Article Background: The aim of this study was to determine whether the presence of disproportionate vertebral bodies is a risk factor for disc herniation (DH). Methods: Sixty-seven consecutive patients (m: 31 f: 36) who underwent lumbar discectomy for symptomatic DH at one level between L3 and S1 were retrospectively included. The last three motion segments (3 × 67 = 201) were assessed on sagittal MRI scans. A disproportionate motion segment was defined as the difference of more than 10% of the antero-posterior diameter of two adjacent endplates. Results: DH was present in 6/67 (9%), 26/67 (38.8%), and 35/67 (52.2%) patients at L3/4, L4/5, and L5/S1, respectively. A total of 14 of 67 patients demonstrated a disproportionate motion segment at the discectomy level (20.9%). A total of 23 of the 201 (11.4%) investigated motion segments met our criteria for a disproportionate motion segment. In our study population, when one of the 201 segments was disproportionate, the positive predictive value (PPV) for DH increased toward the lower segments: the PPV at the L5/S1 level was 83.0%. The odds ratio of disproportion for DH was the highest at the L5/S1 level, with 6.0 ± 0.82 (p = 0.017). Conclusions: The presence of a disproportionate motion segment in the lower spine may lead to a significant higher risk for DH in patients undergoing discectomy. MDPI 2021-07-19 /pmc/articles/PMC8307056/ /pubmed/34300340 http://dx.doi.org/10.3390/jcm10143174 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Läubli, Ralph Brugger, Robin Pirvu, Tatiana Hoppe, Sven Sieroń, Dominik Szyluk, Karol Albers, Christoph E. Christe, Andreas Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title | Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title_full | Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title_fullStr | Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title_full_unstemmed | Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title_short | Disproportionate Vertebral Bodies and Their Impact on Lumbar Disc Herniation |
title_sort | disproportionate vertebral bodies and their impact on lumbar disc herniation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307056/ https://www.ncbi.nlm.nih.gov/pubmed/34300340 http://dx.doi.org/10.3390/jcm10143174 |
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