Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of Salmonella enterica Serovar Typhimurium Infection

Arginase 1 (ARG1) is a cytosolic enzyme that cleaves L-arginine, the substrate of inducible nitric oxide synthase (iNOS), and thereby impairs the control of various intracellular pathogens. Herein, we investigated the role of ARG1 during infection with Salmonella enterica serovar Typhimurium (S.tm)....

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Detalles Bibliográficos
Autores principales: Brigo, Natascha, Pfeifhofer-Obermair, Christa, Tymoszuk, Piotr, Demetz, Egon, Engl, Sabine, Barros-Pinkelnig, Marina, Dichtl, Stefanie, Fischer, Christine, Valente De Souza, Lara, Petzer, Verena, von Raffay, Laura, Hilbe, Richard, Berger, Sylvia, Seifert, Markus, Schleicher, Ulrike, Bogdan, Christian, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307077/
https://www.ncbi.nlm.nih.gov/pubmed/34359992
http://dx.doi.org/10.3390/cells10071823

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