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GSI Treatment Preserves Protein Synthesis in C2C12 Myotubes

It has been demonstrated that inhibiting Notch signaling through γ-secretase inhibitor (GSI) treatment increases myogenesis, AKT/mTOR signaling, and muscle protein synthesis (MPS) in C2C12 myotubes. The purpose of this study was to determine if GSI-mediated effects on myogenesis and MPS are dependen...

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Detalles Bibliográficos
Autores principales:	Huot, Joshua R., Thompson, Brian, McMullen, Charlotte, Marino, Joseph S., Arthur, Susan T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307118/ https://www.ncbi.nlm.nih.gov/pubmed/34359954 http://dx.doi.org/10.3390/cells10071786

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