Inhibition of CREB-CBP Signaling Improves Fibroblast Plasticity for Direct Cardiac Reprogramming

Direct cardiac reprogramming of fibroblasts into induced cardiomyocytes (iCMs) is a promising approach but remains a challenge in heart regeneration. Efforts have focused on improving the efficiency by understanding fundamental mechanisms. One major challenge is that the plasticity of cultured fibro...

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Detalles Bibliográficos
Autores principales: Bektik, Emre, Sun, Yu, Dennis, Adrienne T., Sakon, Phraew, Yang, Dandan, Deschênes, Isabelle, Fu, Ji-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307124/
https://www.ncbi.nlm.nih.gov/pubmed/34206684
http://dx.doi.org/10.3390/cells10071572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307124/
https://www.ncbi.nlm.nih.gov/pubmed/34206684
http://dx.doi.org/10.3390/cells10071572

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