Total Synthesis of Pagoamide A

The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous structural confirmation of pagoamide A.

Detalles Bibliográficos
Autores principales: Wu, Fusong, Yu, Jie, Meng, Jiawei, Guo, Yian, Ye, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307129/
https://www.ncbi.nlm.nih.gov/pubmed/34299497
http://dx.doi.org/10.3390/molecules26144224
Descripción
Sumario:The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous structural confirmation of pagoamide A.

Ejemplares similares