Development and Validation of a Good Manufacturing Process for IL-4-Driven Expansion of Chimeric Cytokine Receptor-Expressing CAR T-Cells

Adoptive cancer immunotherapy using chimeric antigen receptor (CAR) engineered T-cells holds great promise, although several obstacles hinder the efficient generation of cell products under good manufacturing practice (GMP). Patients are often immune compromised, rendering it challenging to produce...

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Detalles Bibliográficos
Autores principales: van Schalkwyk, May C. I., van der Stegen, Sjoukje J. C., Bosshard-Carter, Leticia, Graves, Helen, Papa, Sophie, Parente-Pereira, Ana C., Farzaneh, Farzin, Fisher, Christopher D., Hope, Andrew, Adami, Antonella, Maher, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307141/
https://www.ncbi.nlm.nih.gov/pubmed/34359966
http://dx.doi.org/10.3390/cells10071797

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