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Trafficking to the Cell Surface of Amino Acid Transporter SLC6A14 Upregulated in Cancer Is Controlled by Phosphorylation of SEC24C Protein by AKT Kinase
Cancer cells need a constant supply of nutrients. SLC6A14, an amino acid transporter B(0,+) (ATB(0,+)) that is upregulated in many cancers, transports all but acidic amino acids. In its exit from the endoplasmic reticulum (ER), it is recognized by the SEC24C subunit of coatomer II (COPII) for furthe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307180/ https://www.ncbi.nlm.nih.gov/pubmed/34359969 http://dx.doi.org/10.3390/cells10071800 |