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Identification of Dihydromyricetin and Metabolites in Serum and Brain Associated with Acute Anti-Ethanol Intoxicating Effects in Mice

Dihydromyricetin is a natural bioactive flavonoid with unique GABA(A) receptor activity with a putative mechanism of action to reduce the intoxication effects of ethanol. Although dihydromyricetin’s poor oral bioavailability limits clinical utility, the promise of this mechanism for the treatment of...

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Detalles Bibliográficos
Autores principales: Carry, Eileen, Kshatriya, Dushyant, Silva, Joshua, Davies, Daryl L., Yuan, Bo, Wu, Qingli, Patel, Harna, Park, Elizabeth R., Gilleran, John, Hao, Lihong, Roberge, Jacques, Bello, Nicholas T., Simon, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307506/
https://www.ncbi.nlm.nih.gov/pubmed/34299083
http://dx.doi.org/10.3390/ijms22147460