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Identification of Dihydromyricetin and Metabolites in Serum and Brain Associated with Acute Anti-Ethanol Intoxicating Effects in Mice
Dihydromyricetin is a natural bioactive flavonoid with unique GABA(A) receptor activity with a putative mechanism of action to reduce the intoxication effects of ethanol. Although dihydromyricetin’s poor oral bioavailability limits clinical utility, the promise of this mechanism for the treatment of...
Autores principales: | Carry, Eileen, Kshatriya, Dushyant, Silva, Joshua, Davies, Daryl L., Yuan, Bo, Wu, Qingli, Patel, Harna, Park, Elizabeth R., Gilleran, John, Hao, Lihong, Roberge, Jacques, Bello, Nicholas T., Simon, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307506/ https://www.ncbi.nlm.nih.gov/pubmed/34299083 http://dx.doi.org/10.3390/ijms22147460 |
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