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A Novel Calcium-Dependent Protein Kinase 1 Inhibitor Potently Prevents Toxoplasma gondii Transmission to Foetuses in Mouse

Treatments currently used to prevent congenital toxoplasmosis are non-specific of Toxoplasma gondii and have grievous side effects. To develop a more specific and less toxic drug, we have designed SP230, an imidazo[1,2-b]pyridazine salt targeting the Toxoplasma gondii calcium-dependent protein kinas...

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Detalles Bibliográficos
Autores principales:	Débare, Héloïse, Moiré, Nathalie, Baron, Firmin, Lantier, Louis, Héraut, Bruno, Van Langendonck, Nathalie, Denevault-Sabourin, Caroline, Dimier-Poisson, Isabelle, Debierre-Grockiego, Françoise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307510/ https://www.ncbi.nlm.nih.gov/pubmed/34299478 http://dx.doi.org/10.3390/molecules26144203

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