Cargando…

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System

Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes. In this study, we provide evidence that MMP2 is an essential factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andries, Lien, Masin, Luca, Salinas-Navarro, Manuel, Zaunz, Samantha, Claes, Marie, Bergmans, Steven, Brouwers, Véronique, Lefevere, Evy, Verfaillie, Catherine, Movahedi, Kiavash, De Groef, Lies, Moons, Lieve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307586/ https://www.ncbi.nlm.nih.gov/pubmed/34359839 http://dx.doi.org/10.3390/cells10071672

Ejemplares similares

Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons
por: Andries, Lien, et al.
Publicado: (2023)

Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System
por: Bollaerts, Ilse, et al.
Publicado: (2017)

A novel retinal ganglion cell quantification tool based on deep learning
por: Masin, Luca, et al.
Publicado: (2021)

MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment
por: Van Hove, Inge, et al.
Publicado: (2016)

ROCK inhibition as a novel potential strategy for axonal regeneration in optic neuropathies
por: Hove, Inge Van, et al.
Publicado: (2015)

Matrix metalloproteinases in the mouse retina: a comparative study of expression patterns and MMP antibodies
por: De Groef, Lies, et al.
Publicado: (2015)

Molecular Mechanisms of Neural Circuit Development and Regeneration
por: Moons, Lieve, et al.
Publicado: (2021)

A new microfluidic model to study dendritic remodeling and mitochondrial dynamics during axonal regeneration of adult zebrafish retinal neurons
por: Van Dyck, Annelies, et al.
Publicado: (2023)

Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase
por: De Groef, Lies, et al.
Publicado: (2015)

The age factor in optic nerve regeneration: Intrinsic and extrinsic barriers hinder successful recovery in the short‐living killifish
por: Vanhunsel, Sophie, et al.
Publicado: (2021)

A Fair Assessment of Evaluation Tools for the Murine Microbead Occlusion Model of Glaucoma
por: Claes, Marie, et al.
Publicado: (2021)

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease
por: Veys, Lien, et al.
Publicado: (2021)

Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats
por: Claes, Marie, et al.
Publicado: (2019)

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox
por: Claes, Marie, et al.
Publicado: (2022)

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice
por: De Groef, Lies, et al.
Publicado: (2016)

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish
por: Bollaerts, Ilse, et al.
Publicado: (2019)

Killifish switch towards mammalian-like regeneration upon aging
por: Vanhunsel, Sophie, et al.
Publicado: (2022)

Characterizing microglia activation: a spatial statistics approach to maximize information extraction
por: Davis, Benjamin M., et al.
Publicado: (2017)

Dendritic shrinkage after injury: a cellular killer or a necessity for axonal regeneration?
por: Beckers, An, et al.
Publicado: (2019)

The killifish visual system as an in vivo model to study brain aging and rejuvenation
por: Vanhunsel, Sophie, et al.
Publicado: (2021)

Optic nerve injury-induced regeneration in the adult zebrafish is accompanied by spatiotemporal changes in mitochondrial dynamics
por: Beckers, An, et al.
Publicado: (2022)

Complementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration
por: Lemmens, Kim, et al.
Publicado: (2016)

Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature
por: Claes, Marie, et al.
Publicado: (2022)

Odorant receptors can mediate axonal identity and gene choice via cAMP-independent mechanisms
por: Movahedi, Kiavash, et al.
Publicado: (2016)

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB
por: Dekeyster, Eline, et al.
Publicado: (2015)

Matrix Metalloproteinase 14 in the Zebrafish: An Eye on Retinal and Retinotectal Development
por: Janssens, Els, et al.
Publicado: (2013)

Corticotropin-releasing factor induces functional and structural synaptic remodelling in acute stress
por: Vandael, Dorien, et al.
Publicado: (2021)

The App(NL-G-F) mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research
por: Vandenabeele, Marjan, et al.
Publicado: (2021)

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model
por: Van Bergen, Tine, et al.
Publicado: (2021)

Retinal Ganglion Cells: Global Number, Density and Vulnerability to Glaucomatous Injury in Common Laboratory Mice
por: Claes, Marie, et al.
Publicado: (2022)

Optimization of Whole Mount RNA Multiplexed in situ Hybridization Chain Reaction With Immunohistochemistry, Clearing and Imaging to Visualize Octopus Embryonic Neurogenesis
por: Elagoz, Ali M., et al.
Publicado: (2022)

Long-term plasticity of inhibitory synapses in the hippocampus and spatial learning depends on matrix metalloproteinase 3
por: Wiera, Grzegorz, et al.
Publicado: (2020)

The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome
por: Punapart, Marite, et al.
Publicado: (2021)

Rabs and axonal regeneration
por: Yong, Cheryl Qian Ying, et al.
Publicado: (2019)

Axonal Regeneration by Glycosaminoglycan
por: Sakamoto, Kazuma, et al.
Publicado: (2021)

On the other end of the line: Extracellular vesicle-mediated communication in glaucoma
por: Lucci, Cristiano, et al.
Publicado: (2023)

Time course analysis of sensory axon regeneration in vivo by directly tracing regenerating axons
por: Gao, Yan, et al.
Publicado: (2019)

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype
por: Jagomäe, Toomas, et al.
Publicado: (2021)

Intrinsic control of axon regeneration
por: He, Zhigang
Publicado: (2010)

Protein deacetylases and axonal regeneration
por: Ng, Fanny, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_fgb1s72s1d0nf26nommiolcj27