Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor survival. Age is a major risk factor, and both alveolar epithelial cells and lung fibroblasts in this disease exhibit features of cellular senescence, a hallmark of ageing. Accumulation of fibrotic extracellular matrix (ECM)...

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Detalles Bibliográficos
Autores principales: Blokland, Kaj E. C., Habibie, Habibie, Borghuis, Theo, Teitsma, Greta J., Schuliga, Michael, Melgert, Barbro N., Knight, Darryl A., Brandsma, Corry-Anke, Pouwels, Simon D., Burgess, Janette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307656/
https://www.ncbi.nlm.nih.gov/pubmed/34209854
http://dx.doi.org/10.3390/cells10071628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307656/
https://www.ncbi.nlm.nih.gov/pubmed/34209854
http://dx.doi.org/10.3390/cells10071628

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