Cargando…

Resveratrol Is a Natural Inhibitor of Human Intestinal Mast Cell Activation and Phosphorylation of Mitochondrial ERK1/2 and STAT3

Mast cells play a critical role as main effector cells in allergic and other inflammatory diseases. Usage of anti-inflammatory nutraceuticals could be of interest for affected patients. Resveratrol, a natural polyphenol found in red grapes, is known for its positive properties. Here, we analyzed the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bilotta, Sabrina, Paruchuru, Lakshmi Bhargavi, Feilhauer, Katharina, Köninger, Jörg, Lorentz, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307672/ https://www.ncbi.nlm.nih.gov/pubmed/34299258 http://dx.doi.org/10.3390/ijms22147640

Ejemplares similares

The Critical Role Played by Mitochondrial MITF Serine 73 Phosphorylation in Immunologically Activated Mast Cells
por: Paruchuru, Lakshmi Bhargavi, et al.
Publicado: (2022)

Resveratrol Treatment Prevents Increase of Mast Cells in Both Murine OVA Enteritis and IL-10(−/−) Colitis
por: Bilotta, Sabrina, et al.
Publicado: (2022)

The pLysRS-Ap(4)A Pathway in Mast Cells Regulates the Switch from Host Defense to a Pathological State
por: Govindaraj, Sharmila, et al.
Publicado: (2021)

The Role Played by Mitochondria in FcεRI-Dependent Mast Cell Activation
por: Chelombitko, Maria A., et al.
Publicado: (2020)

Corrigendum: The Role Played by Mitochondria in FcϵRI-Dependent Mast Cell Activation
por: Chelombitko, Maria A., et al.
Publicado: (2020)

Pylorus drainage procedures in thoracoabdominal esophagectomy – a single-center experience and review of the literature
por: Fritz, Stefan, et al.
Publicado: (2018)

Resection of benign side-branch intraductal papillary mucinous neoplasm of the pancreas—is long term follow-up indicated?: A case report and review of the literature
por: Fritz, Stefan, et al.
Publicado: (2018)

The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation
por: Gough, Daniel J., et al.
Publicado: (2013)

The SNARE Machinery in Mast Cell Secretion
por: Lorentz, Axel, et al.
Publicado: (2012)

Correction: The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation
por: Gough, Daniel J., et al.
Publicado: (2013)

Intraductal tubular papillary neoplasm (ITPN), a novel entity of pancreatic epithelial neoplasms and precursor of cancer: A case report and review of the literature
por: Fritz, Stefan, et al.
Publicado: (2019)

Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies?
por: Kaag, Sina, et al.
Publicado: (2023)

Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells
por: Peter, Barbara, et al.
Publicado: (2017)

Interferon-γ regulates growth and controls Fcγ receptor expression and activation in human intestinal mast cells
por: Sellge, Gernot, et al.
Publicado: (2014)

The Circadian Clock Drives Mast Cell Functions in Allergic Reactions
por: Christ, Pia, et al.
Publicado: (2018)

Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism
por: Huang, Yuanyuan, et al.
Publicado: (2021)

Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3(Tyr705) phosphorylation
por: Sun, Xiaodong, et al.
Publicado: (2020)

Effects of Resveratrol on Thymic Stromal Lymphopoietin Expression in Mast Cells
por: Moon, Phil-Dong, et al.
Publicado: (2020)

Ataxin-3, The Spinocerebellar Ataxia Type 3 Neurodegenerative Disorder Protein, Affects Mast Cell Functions
por: Sowa, Anna S., et al.
Publicado: (2022)

hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts
por: Wang, Yifei, et al.
Publicado: (2023)

Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2
por: Kato, Akihisa, et al.
Publicado: (2015)

S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis
por: Feng, Xiujing, et al.
Publicado: (2013)

Critical Role for Mast Cell Stat5 Activity in Skin Inflammation
por: Ando, Tomoaki, et al.
Publicado: (2014)

SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
por: Bagul, Pankaj K., et al.
Publicado: (2018)

6-O-angeloylplenolin inhibits anti-IgE-stimulated human mast cell activation via suppressing calcium influx and ERK phosphorylation
por: Yu, Yangyang, et al.
Publicado: (2022)

Role of STAT3 Phosphorylation in Ethanol-Mediated Proliferation of Breast Cancer Cells
por: Narayanan, Poornima devi, et al.
Publicado: (2016)

Autophagy proteins regulate ERK phosphorylation
por: Martinez-Lopez, Nuria, et al.
Publicado: (2013)

Phase plane dynamics of ERK phosphorylation
por: Shvartsman, Stanislav Y., et al.
Publicado: (2023)

Mitochondrial ROS production and subsequent ERK phosphorylation are necessary for temperature preconditioning of isolated ventricular myocytes
por: Bhagatte, Y, et al.
Publicado: (2012)

The Distinct Effects of the Mitochondria-Targeted STAT3 Inhibitors Mitocur-1 and Mitocur-3 on Mast Cell and Mitochondrial Functions
por: Pavlyuchenkova, Anastasia N., et al.
Publicado: (2023)

STAT2 phosphorylation and signaling
por: Steen, Håkan C, et al.
Publicado: (2013)

Resveratrol in Intestinal Health and Disease: Focusing on Intestinal Barrier
por: Wang, Youxia, et al.
Publicado: (2022)

EGFR-mediated tumor immunoescape: The imbalance between phosphorylated STAT1 and phosphorylated STAT3
por: Concha-Benavente, Fernando, et al.
Publicado: (2013)

Resveratrol Protects against Skin Inflammation through Inhibition of Mast Cell, Sphingosine Kinase-1, Stat3 and NF-κB p65 Signaling Activation in Mice
por: Carlucci, Christopher D., et al.
Publicado: (2023)

Resveratrol and STAT inhibitor enhance autophagy in ovarian cancer cells
por: Zhong, L-X, et al.
Publicado: (2016)

ITF promotes migration of intestinal epithelial cells through crosstalk between the ERK and JAK/STAT3 pathways
por: Le, Juan, et al.
Publicado: (2016)

Stoichiometry of STAT3 and Mitochondrial Proteins: IMPLICATIONS FOR THE REGULATION OF OXIDATIVE PHOSPHORYLATION BY PROTEIN-PROTEIN INTERACTIONS
por: Phillips, Darci, et al.
Publicado: (2010)

The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis
por: Tateno, Toru, et al.
Publicado: (2011)

Phosphorylated resveratrol as a protein aggregation suppressor in vitro and in vivo
por: Mehringer, Johannes, et al.
Publicado: (2022)

ERK Phosphorylation Regulates Sleep and Plasticity in Drosophila
por: Vanderheyden, William M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0mc8qqbitbfopahgl8q5h1ftpe