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A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis?
The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307918/ https://www.ncbi.nlm.nih.gov/pubmed/34209585 http://dx.doi.org/10.3390/life11070627 |
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author | Salgado-Boquete, Laura Carrascosa, José Manuel Llamas-Velasco, Mar Ruiz-Villaverde, Ricardo de la Cueva, Pablo Belinchón, Isabel |
author_facet | Salgado-Boquete, Laura Carrascosa, José Manuel Llamas-Velasco, Mar Ruiz-Villaverde, Ricardo de la Cueva, Pablo Belinchón, Isabel |
author_sort | Salgado-Boquete, Laura |
collection | PubMed |
description | The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe. |
format | Online Article Text |
id | pubmed-8307918 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83079182021-07-25 A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? Salgado-Boquete, Laura Carrascosa, José Manuel Llamas-Velasco, Mar Ruiz-Villaverde, Ricardo de la Cueva, Pablo Belinchón, Isabel Life (Basel) Article The purpose of this study is to propose a ranking system for the severity of psoriasis. The consensus method of selecting the indices to include and the classification of real patient profiles by an expert panel to create a gold standard of severity were used. The performance of potential cut-offs was evaluated to create a ranking algorithm. The combined use of PASI, BSA, and sPGA may allow the classification of the severity of psoriatic patients. The final algorithm identifies severe patients in a single step (2 out 3 are met: PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3), while two steps are required for mild ((2 out 3 are met: PASI ≤ 3 or BSA ≤ 5 or sPGA ≤ 2) and DLQI < 5) and moderate forms (the patient does not meet 2 out 3 (PASI ≥ 11 or BSA ≥ 10 or sPGA ≥ 3) but has a DLQI ≥ 5. A ranking algorithm is presented, consisting of different measures of disease which classifies psoriatic patients into three categories: mild, moderate, and severe. MDPI 2021-06-29 /pmc/articles/PMC8307918/ /pubmed/34209585 http://dx.doi.org/10.3390/life11070627 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Salgado-Boquete, Laura Carrascosa, José Manuel Llamas-Velasco, Mar Ruiz-Villaverde, Ricardo de la Cueva, Pablo Belinchón, Isabel A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title_full | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title_fullStr | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title_full_unstemmed | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title_short | A New Classification of the Severity of Psoriasis: What’s Moderate Psoriasis? |
title_sort | new classification of the severity of psoriasis: what’s moderate psoriasis? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307918/ https://www.ncbi.nlm.nih.gov/pubmed/34209585 http://dx.doi.org/10.3390/life11070627 |
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