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Evaluation and Optimization of Poly-d-Lysine as a Non-Natural Cationic Polypeptide for Gene Transfer in Neuroblastoma Cells

Cationic polypeptides and cationic polymers have cell-penetrating capacities and have been used in gene transfer studies. In this study, we investigate the capability of a polymer of d-lysine (PDL), a chiral form of α–Poly-lysine, as a possible nonviral vector for releasing genetic materials to neur...

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Detalles Bibliográficos
Autores principales: Sanchez-Martos, Miguel, Martinez-Navarrete, Gema, Bernabeu-Zornoza, Adela, Humphreys, Lawrence, Fernandez, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308159/
https://www.ncbi.nlm.nih.gov/pubmed/34361142
http://dx.doi.org/10.3390/nano11071756