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Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia

Studies on vitamin D status and its determinants in growing children in countries with ample sunshine such as Malaysia have been limited. The aim of our study was to determine factors associated with serum 25(OH)D concentrations such as lifestyle, dietary intake, anthropometry, and body composition...

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Autores principales: Chee, Winnie Siew Swee, Chang, Chung Yuan, Arasu, Kanimolli, Wong, Soon Yee, Ong, Shu Hwa, Yang, Wai Yew, Chong, Megan Hueh Zan, Mavinkurve, Meenal, Khoo, Erwin Jiayuan, Chinna, Karuthan, Weaver, Connie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308301/
https://www.ncbi.nlm.nih.gov/pubmed/34202743
http://dx.doi.org/10.3390/nu13072175
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author Chee, Winnie Siew Swee
Chang, Chung Yuan
Arasu, Kanimolli
Wong, Soon Yee
Ong, Shu Hwa
Yang, Wai Yew
Chong, Megan Hueh Zan
Mavinkurve, Meenal
Khoo, Erwin Jiayuan
Chinna, Karuthan
Weaver, Connie M.
author_facet Chee, Winnie Siew Swee
Chang, Chung Yuan
Arasu, Kanimolli
Wong, Soon Yee
Ong, Shu Hwa
Yang, Wai Yew
Chong, Megan Hueh Zan
Mavinkurve, Meenal
Khoo, Erwin Jiayuan
Chinna, Karuthan
Weaver, Connie M.
author_sort Chee, Winnie Siew Swee
collection PubMed
description Studies on vitamin D status and its determinants in growing children in countries with ample sunshine such as Malaysia have been limited. The aim of our study was to determine factors associated with serum 25(OH)D concentrations such as lifestyle, dietary intake, anthropometry, and body composition in 243 pre-adolescent Malaysian children from low-income families living in Kuala Lumpur. This cross-sectional study measured bone density and body composition using dual-energy X-ray absorptiometry (DXA), while serum 25(OH)D was measured using LC–MS/MS. Time spent outdoors, body surface area exposed to sunlight, dietary intake, and physical activity level were assessed using questionnaires. Multiple linear regression and stepwise analysis were performed to identify significant predictors for serum 25(OH)D. About 69.4% had 25(OH)D < 50 nmol/L, and 18.9% were vitamin-D-deficient with 25(OH)D < 30 nmol/L. Girls had a nine-fold higher prevalence of vitamin D deficiency than boys. Body surface area exposed to sunlight, Sun Index, and fat mass were significant predictors of 25(OH)D concentrations in this population. Modifiable lifestyle factors such as sun exposure and reducing obesity are important public health guidance to ensure optimal vitamin D status in these children.
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spelling pubmed-83083012021-07-25 Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia Chee, Winnie Siew Swee Chang, Chung Yuan Arasu, Kanimolli Wong, Soon Yee Ong, Shu Hwa Yang, Wai Yew Chong, Megan Hueh Zan Mavinkurve, Meenal Khoo, Erwin Jiayuan Chinna, Karuthan Weaver, Connie M. Nutrients Article Studies on vitamin D status and its determinants in growing children in countries with ample sunshine such as Malaysia have been limited. The aim of our study was to determine factors associated with serum 25(OH)D concentrations such as lifestyle, dietary intake, anthropometry, and body composition in 243 pre-adolescent Malaysian children from low-income families living in Kuala Lumpur. This cross-sectional study measured bone density and body composition using dual-energy X-ray absorptiometry (DXA), while serum 25(OH)D was measured using LC–MS/MS. Time spent outdoors, body surface area exposed to sunlight, dietary intake, and physical activity level were assessed using questionnaires. Multiple linear regression and stepwise analysis were performed to identify significant predictors for serum 25(OH)D. About 69.4% had 25(OH)D < 50 nmol/L, and 18.9% were vitamin-D-deficient with 25(OH)D < 30 nmol/L. Girls had a nine-fold higher prevalence of vitamin D deficiency than boys. Body surface area exposed to sunlight, Sun Index, and fat mass were significant predictors of 25(OH)D concentrations in this population. Modifiable lifestyle factors such as sun exposure and reducing obesity are important public health guidance to ensure optimal vitamin D status in these children. MDPI 2021-06-24 /pmc/articles/PMC8308301/ /pubmed/34202743 http://dx.doi.org/10.3390/nu13072175 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chee, Winnie Siew Swee
Chang, Chung Yuan
Arasu, Kanimolli
Wong, Soon Yee
Ong, Shu Hwa
Yang, Wai Yew
Chong, Megan Hueh Zan
Mavinkurve, Meenal
Khoo, Erwin Jiayuan
Chinna, Karuthan
Weaver, Connie M.
Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title_full Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title_fullStr Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title_full_unstemmed Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title_short Vitamin D Status Is Associated with Modifiable Lifestyle Factors in Pre-Adolescent Children Living in Urban Kuala Lumpur, Malaysia
title_sort vitamin d status is associated with modifiable lifestyle factors in pre-adolescent children living in urban kuala lumpur, malaysia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308301/
https://www.ncbi.nlm.nih.gov/pubmed/34202743
http://dx.doi.org/10.3390/nu13072175
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