Cargando…

Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic

The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The cu...

Descripción completa

Detalles Bibliográficos
Autores principales: Asdaq, Syed Mohammed Basheeruddin, Ikbal, Abu Md Ashif, Sahu, Ram Kumar, Bhattacharjee, Bedanta, Paul, Tirna, Deka, Bhargab, Fattepur, Santosh, Widyowati, Retno, Vijaya, Joshi, Al mohaini, Mohammed, Alsalman, Abdulkhaliq J., Imran, Mohd., Nagaraja, Sreeharsha, Nair, Anroop B., Attimarad, Mahesh, Venugopala, Katharigatta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308419/
https://www.ncbi.nlm.nih.gov/pubmed/34361227
http://dx.doi.org/10.3390/nano11071841
_version_ 1783728276633550848
author Asdaq, Syed Mohammed Basheeruddin
Ikbal, Abu Md Ashif
Sahu, Ram Kumar
Bhattacharjee, Bedanta
Paul, Tirna
Deka, Bhargab
Fattepur, Santosh
Widyowati, Retno
Vijaya, Joshi
Al mohaini, Mohammed
Alsalman, Abdulkhaliq J.
Imran, Mohd.
Nagaraja, Sreeharsha
Nair, Anroop B.
Attimarad, Mahesh
Venugopala, Katharigatta N.
author_facet Asdaq, Syed Mohammed Basheeruddin
Ikbal, Abu Md Ashif
Sahu, Ram Kumar
Bhattacharjee, Bedanta
Paul, Tirna
Deka, Bhargab
Fattepur, Santosh
Widyowati, Retno
Vijaya, Joshi
Al mohaini, Mohammed
Alsalman, Abdulkhaliq J.
Imran, Mohd.
Nagaraja, Sreeharsha
Nair, Anroop B.
Attimarad, Mahesh
Venugopala, Katharigatta N.
author_sort Asdaq, Syed Mohammed Basheeruddin
collection PubMed
description The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.
format Online
Article
Text
id pubmed-8308419
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83084192021-07-25 Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic Asdaq, Syed Mohammed Basheeruddin Ikbal, Abu Md Ashif Sahu, Ram Kumar Bhattacharjee, Bedanta Paul, Tirna Deka, Bhargab Fattepur, Santosh Widyowati, Retno Vijaya, Joshi Al mohaini, Mohammed Alsalman, Abdulkhaliq J. Imran, Mohd. Nagaraja, Sreeharsha Nair, Anroop B. Attimarad, Mahesh Venugopala, Katharigatta N. Nanomaterials (Basel) Review The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight. MDPI 2021-07-16 /pmc/articles/PMC8308419/ /pubmed/34361227 http://dx.doi.org/10.3390/nano11071841 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Asdaq, Syed Mohammed Basheeruddin
Ikbal, Abu Md Ashif
Sahu, Ram Kumar
Bhattacharjee, Bedanta
Paul, Tirna
Deka, Bhargab
Fattepur, Santosh
Widyowati, Retno
Vijaya, Joshi
Al mohaini, Mohammed
Alsalman, Abdulkhaliq J.
Imran, Mohd.
Nagaraja, Sreeharsha
Nair, Anroop B.
Attimarad, Mahesh
Venugopala, Katharigatta N.
Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title_full Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title_fullStr Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title_full_unstemmed Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title_short Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
title_sort nanotechnology integration for sars-cov-2 diagnosis and treatment: an approach to preventing pandemic
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308419/
https://www.ncbi.nlm.nih.gov/pubmed/34361227
http://dx.doi.org/10.3390/nano11071841
work_keys_str_mv AT asdaqsyedmohammedbasheeruddin nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT ikbalabumdashif nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT sahuramkumar nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT bhattacharjeebedanta nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT paultirna nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT dekabhargab nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT fattepursantosh nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT widyowatiretno nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT vijayajoshi nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT almohainimohammed nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT alsalmanabdulkhaliqj nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT imranmohd nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT nagarajasreeharsha nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT nairanroopb nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT attimaradmahesh nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic
AT venugopalakatharigattan nanotechnologyintegrationforsarscov2diagnosisandtreatmentanapproachtopreventingpandemic