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Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic
The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The cu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308419/ https://www.ncbi.nlm.nih.gov/pubmed/34361227 http://dx.doi.org/10.3390/nano11071841 |
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author | Asdaq, Syed Mohammed Basheeruddin Ikbal, Abu Md Ashif Sahu, Ram Kumar Bhattacharjee, Bedanta Paul, Tirna Deka, Bhargab Fattepur, Santosh Widyowati, Retno Vijaya, Joshi Al mohaini, Mohammed Alsalman, Abdulkhaliq J. Imran, Mohd. Nagaraja, Sreeharsha Nair, Anroop B. Attimarad, Mahesh Venugopala, Katharigatta N. |
author_facet | Asdaq, Syed Mohammed Basheeruddin Ikbal, Abu Md Ashif Sahu, Ram Kumar Bhattacharjee, Bedanta Paul, Tirna Deka, Bhargab Fattepur, Santosh Widyowati, Retno Vijaya, Joshi Al mohaini, Mohammed Alsalman, Abdulkhaliq J. Imran, Mohd. Nagaraja, Sreeharsha Nair, Anroop B. Attimarad, Mahesh Venugopala, Katharigatta N. |
author_sort | Asdaq, Syed Mohammed Basheeruddin |
collection | PubMed |
description | The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight. |
format | Online Article Text |
id | pubmed-8308419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83084192021-07-25 Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic Asdaq, Syed Mohammed Basheeruddin Ikbal, Abu Md Ashif Sahu, Ram Kumar Bhattacharjee, Bedanta Paul, Tirna Deka, Bhargab Fattepur, Santosh Widyowati, Retno Vijaya, Joshi Al mohaini, Mohammed Alsalman, Abdulkhaliq J. Imran, Mohd. Nagaraja, Sreeharsha Nair, Anroop B. Attimarad, Mahesh Venugopala, Katharigatta N. Nanomaterials (Basel) Review The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight. MDPI 2021-07-16 /pmc/articles/PMC8308419/ /pubmed/34361227 http://dx.doi.org/10.3390/nano11071841 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Asdaq, Syed Mohammed Basheeruddin Ikbal, Abu Md Ashif Sahu, Ram Kumar Bhattacharjee, Bedanta Paul, Tirna Deka, Bhargab Fattepur, Santosh Widyowati, Retno Vijaya, Joshi Al mohaini, Mohammed Alsalman, Abdulkhaliq J. Imran, Mohd. Nagaraja, Sreeharsha Nair, Anroop B. Attimarad, Mahesh Venugopala, Katharigatta N. Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title | Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title_full | Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title_fullStr | Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title_full_unstemmed | Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title_short | Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic |
title_sort | nanotechnology integration for sars-cov-2 diagnosis and treatment: an approach to preventing pandemic |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308419/ https://www.ncbi.nlm.nih.gov/pubmed/34361227 http://dx.doi.org/10.3390/nano11071841 |
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