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Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients

Background & Aims: SARS-CoV2 infection is associated with an increased risk of malnutrition. Although there are numerous screening and nutritional management protocols for malnutrition, only few studies have reported nutritional evolution after COVID-19. The objectives of this study were to desc...

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Autores principales: Bedock, Dorothée, Couffignal, Julie, Bel Lassen, Pierre, Soares, Leila, Mathian, Alexis, Fadlallah, Jehane P., Amoura, Zahir, Oppert, Jean-Michel, Faucher, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308434/
https://www.ncbi.nlm.nih.gov/pubmed/34209229
http://dx.doi.org/10.3390/nu13072276
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author Bedock, Dorothée
Couffignal, Julie
Bel Lassen, Pierre
Soares, Leila
Mathian, Alexis
Fadlallah, Jehane P.
Amoura, Zahir
Oppert, Jean-Michel
Faucher, Pauline
author_facet Bedock, Dorothée
Couffignal, Julie
Bel Lassen, Pierre
Soares, Leila
Mathian, Alexis
Fadlallah, Jehane P.
Amoura, Zahir
Oppert, Jean-Michel
Faucher, Pauline
author_sort Bedock, Dorothée
collection PubMed
description Background & Aims: SARS-CoV2 infection is associated with an increased risk of malnutrition. Although there are numerous screening and nutritional management protocols for malnutrition, only few studies have reported nutritional evolution after COVID-19. The objectives of this study were to describe the evolution of nutritional parameters between admission and 30 days after hospital discharge, and to determine predictive factors of poor nutritional outcome after recovery in adult COVID-19 patients. Methods: In this observational longitudinal study, we report findings after discharge in 91 out of 114 patients initially admitted for COVID-19 who received early nutritional management. Nutritional status was defined using GLIM criteria and compared between admission and day 30 after discharge. Baseline predictors of nutritional status at day 30 were assessed using logistic regression. Results: Thirty days after discharge, 28.6% of patients hospitalized for COVID-19 were malnourished, compared to 42.3% at admission. Half of malnourished patients (53%) at admission recovered a normal nutritional status after discharge. Weight trajectories were heterogeneous and differed if patients had been transferred to an intensive care unit (ICU) during hospitalization (p = 0.025). High oxygen requirement during hospitalization (invasive ventilation p = 0.016 (OR 8.3 [1.6–61.2]) and/or oxygen therapy over 5 L/min p = 0.021 (OR 3.2 [1.2–8.9]) were strong predictors of malnutrition one month after discharge. Conclusions: With early nutritional management, most patients hospitalized for COVID-19 improved nutritional parameters after discharge. These findings emphasize the importance of nutritional care in COVID-19 patients hospitalized in medicine departments, especially in those transferred from ICU.
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spelling pubmed-83084342021-07-25 Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients Bedock, Dorothée Couffignal, Julie Bel Lassen, Pierre Soares, Leila Mathian, Alexis Fadlallah, Jehane P. Amoura, Zahir Oppert, Jean-Michel Faucher, Pauline Nutrients Article Background & Aims: SARS-CoV2 infection is associated with an increased risk of malnutrition. Although there are numerous screening and nutritional management protocols for malnutrition, only few studies have reported nutritional evolution after COVID-19. The objectives of this study were to describe the evolution of nutritional parameters between admission and 30 days after hospital discharge, and to determine predictive factors of poor nutritional outcome after recovery in adult COVID-19 patients. Methods: In this observational longitudinal study, we report findings after discharge in 91 out of 114 patients initially admitted for COVID-19 who received early nutritional management. Nutritional status was defined using GLIM criteria and compared between admission and day 30 after discharge. Baseline predictors of nutritional status at day 30 were assessed using logistic regression. Results: Thirty days after discharge, 28.6% of patients hospitalized for COVID-19 were malnourished, compared to 42.3% at admission. Half of malnourished patients (53%) at admission recovered a normal nutritional status after discharge. Weight trajectories were heterogeneous and differed if patients had been transferred to an intensive care unit (ICU) during hospitalization (p = 0.025). High oxygen requirement during hospitalization (invasive ventilation p = 0.016 (OR 8.3 [1.6–61.2]) and/or oxygen therapy over 5 L/min p = 0.021 (OR 3.2 [1.2–8.9]) were strong predictors of malnutrition one month after discharge. Conclusions: With early nutritional management, most patients hospitalized for COVID-19 improved nutritional parameters after discharge. These findings emphasize the importance of nutritional care in COVID-19 patients hospitalized in medicine departments, especially in those transferred from ICU. MDPI 2021-06-30 /pmc/articles/PMC8308434/ /pubmed/34209229 http://dx.doi.org/10.3390/nu13072276 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bedock, Dorothée
Couffignal, Julie
Bel Lassen, Pierre
Soares, Leila
Mathian, Alexis
Fadlallah, Jehane P.
Amoura, Zahir
Oppert, Jean-Michel
Faucher, Pauline
Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title_full Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title_fullStr Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title_full_unstemmed Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title_short Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients
title_sort evolution of nutritional status after early nutritional management in covid-19 hospitalized patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308434/
https://www.ncbi.nlm.nih.gov/pubmed/34209229
http://dx.doi.org/10.3390/nu13072276
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