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Comparative EPR Study on the Scavenging Effect of Methotrexate with the Isomers of Its Photoswitchable Derivative

The scavenging effect of the antimetabolite dihydrofolate reductase inhibitor methotrexate (MTX) and the isomers of its photoswitchable derivate, cis- and trans-phototrexate (PHX), have been compared by ESR spectroscopy, with the application of a cyclic hydroxylamine spin probe. The results showed t...

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Detalles Bibliográficos
Autores principales: Preisz, Zsolt, Hartvig, Nóra, Bognár, Balázs, Kálai, Tamás, Kunsági-Máté, Sándor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308517/
https://www.ncbi.nlm.nih.gov/pubmed/34358091
http://dx.doi.org/10.3390/ph14070665