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3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish
Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vasculature, plays critical roles in disease, including in cancer metastasis and chronic inflammation. Preclinical and recent clinical studies have now demonstrated therapeutic utility for several anti-lymphangiogenic agents...
Autores principales: | Okuda, Kazuhide S., Ng, Mei Fong, Ruslan, Nur Faizah, Bower, Neil I., Song, Dedrick Soon Seng, Chen, Huijun, Baek, Sungmin, Crosier, Philip S., Koltowska, Katarzyna, Astin, Jonathan W., Tan, Pei Jean, Hogan, Benjamin M., Patel, Vyomesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308560/ https://www.ncbi.nlm.nih.gov/pubmed/34206901 http://dx.doi.org/10.3390/ph14070614 |
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