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Protective Effects of Irbesartan, an Angiotensin Receptor Blocker with PPARγ Agonistic Activity, against Estradiol Benzoate-Induced Endometrial Hyperplasia and Atypia in Female Rats via Modulation of TNFα/Survivin Pathway

Endometrial hyperplasia (EH) is a common gynecological problem and may progress to carcinoma. Early detection and management of EH are mandatory for the prevention of endometrial cancer. Activation of the renin–angiotensin system and angiotensin II signaling are involved in the progression of precan...

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Detalles Bibliográficos
Autores principales: Morsy, Mohamed A., Abdelraheem, Wedad M., El-Hussieny, Maram, Refaie, Marwa M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308641/
https://www.ncbi.nlm.nih.gov/pubmed/34358075
http://dx.doi.org/10.3390/ph14070649