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Therapeutic Drug Monitoring of Busulfan in Patients Undergoing Hematopoietic Cell Transplantation: A Pilot Single-Center Study in Taiwan

Busulfan has been used as a conditioning regimen in allogeneic hematopoietic cell stem transplantation (HSCT). Owing to a large inter-individual variation in pharmacokinetics, therapeutic drug monitoring (TDM)-guided busulfan dosing is necessary to reduce graft failure and relapse rate. As there exi...

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Detalles Bibliográficos
Autores principales: Chen, Rong-Long, Fang, Li-Hua, Yang, Xin-Yi, El Amrani, Mohsin, Uijtendaal, Esther Veronique, Chen, Yen-Fu, Ku, Wei-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308703/
https://www.ncbi.nlm.nih.gov/pubmed/34206798
http://dx.doi.org/10.3390/ph14070613