α-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFα/IFNγ Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube

There is ongoing debate as to whether or not α-hydroxyisocaproic acid (HICA) positively regulates skeletal muscle protein synthesis resulting in the gain or maintenance of skeletal muscle. We investigated the effects of HICA on mouse C2C12 myotubes under normal conditions and during cachexia induced...

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Detalles Bibliográficos
Autores principales: Sumi, Koichiro, Sakuda, Misato, Munakata, Kinuyo, Nakamura, Kentaro, Ashida, Kinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308709/
https://www.ncbi.nlm.nih.gov/pubmed/34371902
http://dx.doi.org/10.3390/nu13072391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308709/
https://www.ncbi.nlm.nih.gov/pubmed/34371902
http://dx.doi.org/10.3390/nu13072391

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