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Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors

The purpose of this study was to examine the independent and joint associations of acid-producing diets and depressive symptoms with physical health among breast cancer survivors. We studied a cohort of 2944 early stage breast cancer survivors who provided dietary, physical health, demographic, and...

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Autores principales: Tessou, K. Daniel, Lemus, Hector, Hsu, Fang-Chi, Pierce, John, Hong, Suzi, Brown, Lauren, Wu, Tianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308757/
https://www.ncbi.nlm.nih.gov/pubmed/34371931
http://dx.doi.org/10.3390/nu13072422
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author Tessou, K. Daniel
Lemus, Hector
Hsu, Fang-Chi
Pierce, John
Hong, Suzi
Brown, Lauren
Wu, Tianying
author_facet Tessou, K. Daniel
Lemus, Hector
Hsu, Fang-Chi
Pierce, John
Hong, Suzi
Brown, Lauren
Wu, Tianying
author_sort Tessou, K. Daniel
collection PubMed
description The purpose of this study was to examine the independent and joint associations of acid-producing diets and depressive symptoms with physical health among breast cancer survivors. We studied a cohort of 2944 early stage breast cancer survivors who provided dietary, physical health, demographic, and lifestyle information at baseline, year 1, and year 4. We assessed the intakes of acid-producing diets via two commonly used dietary acid load scores: potential renal acid load (PRAL) and net endogenous acid production (NEAP). Physical health was measured using the Rand 36-Item Short Form Health Survey (SF-36), consisting of physical functioning, role limitation due to physical function, bodily pain, general health, and overall physical health subscales. Increased dietary acid load and depression were each independently and significantly associated with reduced physical health subscales and overall physical health. Further, dietary acid load and depression were jointly associated with worse physical health. For instance, depressed women with dietary acid load higher than median reported 2.75 times the risk (odds ratio = 2.75; 95% confidence interval: 2.18–3.47) of reduced physical function and 3.10 times the risk of poor physical health (odds ratio = 3.10; 95% confidence interval: 2.53–3.80) compared to non-depressed women with dietary acid load lower than median. Our results highlight the need of controlling acid-producing diets and the access of mental care for breast cancer survivors.
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spelling pubmed-83087572021-07-25 Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors Tessou, K. Daniel Lemus, Hector Hsu, Fang-Chi Pierce, John Hong, Suzi Brown, Lauren Wu, Tianying Nutrients Article The purpose of this study was to examine the independent and joint associations of acid-producing diets and depressive symptoms with physical health among breast cancer survivors. We studied a cohort of 2944 early stage breast cancer survivors who provided dietary, physical health, demographic, and lifestyle information at baseline, year 1, and year 4. We assessed the intakes of acid-producing diets via two commonly used dietary acid load scores: potential renal acid load (PRAL) and net endogenous acid production (NEAP). Physical health was measured using the Rand 36-Item Short Form Health Survey (SF-36), consisting of physical functioning, role limitation due to physical function, bodily pain, general health, and overall physical health subscales. Increased dietary acid load and depression were each independently and significantly associated with reduced physical health subscales and overall physical health. Further, dietary acid load and depression were jointly associated with worse physical health. For instance, depressed women with dietary acid load higher than median reported 2.75 times the risk (odds ratio = 2.75; 95% confidence interval: 2.18–3.47) of reduced physical function and 3.10 times the risk of poor physical health (odds ratio = 3.10; 95% confidence interval: 2.53–3.80) compared to non-depressed women with dietary acid load lower than median. Our results highlight the need of controlling acid-producing diets and the access of mental care for breast cancer survivors. MDPI 2021-07-15 /pmc/articles/PMC8308757/ /pubmed/34371931 http://dx.doi.org/10.3390/nu13072422 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tessou, K. Daniel
Lemus, Hector
Hsu, Fang-Chi
Pierce, John
Hong, Suzi
Brown, Lauren
Wu, Tianying
Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title_full Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title_fullStr Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title_full_unstemmed Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title_short Independent and Joint Impacts of Acid-Producing Diets and Depression on Physical Health among Breast Cancer Survivors
title_sort independent and joint impacts of acid-producing diets and depression on physical health among breast cancer survivors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308757/
https://www.ncbi.nlm.nih.gov/pubmed/34371931
http://dx.doi.org/10.3390/nu13072422
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