Cargando…

ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential

On 11 March 2020, the World Health Organization (WHO) classified the Coronavirus Disease 2019 (COVID-19) as a global pandemic, which tested healthcare systems, administrations, and treatment ingenuity across the world. COVID-19 is caused by the novel beta coronavirus Severe Acute Respiratory Syndrom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deb, Subrata, Reeves, Anthony Allen, Hopefl, Robert, Bejusca, Rebecca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308800/ https://www.ncbi.nlm.nih.gov/pubmed/34358081 http://dx.doi.org/10.3390/ph14070655

Ejemplares similares

Simulation of Physicochemical and Pharmacokinetic Properties of Vitamin D(3) and Its Natural Derivatives
por: Deb, Subrata, et al.
Publicado: (2020)

The evaluation of ADME and pharmacokinetic properties of decoquinate derivatives for the treatment of malaria
por: Watson, Daniel J., et al.
Publicado: (2022)

ADME Considerations and Bioanalytical Strategies for Pharmacokinetic Assessments of Antibody-Drug Conjugates
por: Mou, Si, et al.
Publicado: (2018)

Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development
por: Tibbitts, Jay, et al.
Publicado: (2015)

ADME, Pharmacokinetic Scaling, Pharmacodynamic and Prediction of Human Dose and Regimen of Novel Antiviral Drugs
por: Chaira, Tridib, et al.
Publicado: (2023)

ADME-Space: a new tool for medicinal chemists to explore ADME properties
por: Bocci, Giovanni, et al.
Publicado: (2017)

538. Clinical Evaluation of Drug-drug Interactions with Remdesivir
por: Peng, Chi-Chi, et al.
Publicado: (2023)

Metabolic profiling, ADME pharmacokinetics, molecular docking studies and antibacterial potential of Phyllantus muellerianus leaves
por: Obuotor, Tolulope M., et al.
Publicado: (2021)

Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor
por: Humeniuk, Rita, et al.
Publicado: (2021)

Potential Interactions of Remdesivir with Pulmonary Drugs: a Covid-19 Perspective
por: Gandhi, Zainab, et al.
Publicado: (2020)

OSWG Recommended Approaches to the Nonclinical Pharmacokinetic (ADME) Characterization of Therapeutic Oligonucleotides
por: Berman, Cindy L., et al.
Publicado: (2023)

Calcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic Interactions
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2016)

Integration Analysis of Pharmacokinetics and Metabolomics to Predict Metabolic Phenotype and Drug Exposure of Remdesivir
por: Du, Ping, et al.
Publicado: (2022)

Matrine reverses the drug resistance of K562/ADM cells to ADM and VCR via promoting autophagy
por: Li, Zhao, et al.
Publicado: (2020)

Emergency Use Authorization for Remdesivir and Its Potential Implications
por: Ochoa Chaar, Cassius Iyad, et al.
Publicado: (2020)

An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives
por: Tanner, Lloyd, et al.
Publicado: (2019)

The use of quantum chemistry in the prediction of ADME-Tox properties
por: Van Damme, S, et al.
Publicado: (2008)

Antistaphylococcal Activities and ADME-Related Properties of Chlorinated Arylcarbamoylnaphthalenylcarbamates
por: Gonec, Tomas, et al.
Publicado: (2022)

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
por: Daina, Antoine, et al.
Publicado: (2017)

Comparison of Pinoresinol and its Diglucoside on their ADME Properties and Vasorelaxant Effects on Phenylephrine-Induced Model
por: Pu, Yiqiong, et al.
Publicado: (2021)

In vivo pharmacokinetic study of remdesivir dry powder for inhalation in hamsters
por: Sahakijpijarn, Sawittree, et al.
Publicado: (2021)

Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants
por: Humeniuk, Rita, et al.
Publicado: (2023)

Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19
por: Liu, Xiaomei I., et al.
Publicado: (2022)

ADME SARfari: comparative genomics of drug metabolizing systems
por: Davies, Mark, et al.
Publicado: (2015)

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data
por: James, Alexander D., et al.
Publicado: (2020)

In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities
por: Han, Ying, et al.
Publicado: (2019)

What Do We Know About Remdesivir Drug Interactions?
por: Yang, Katherine
Publicado: (2020)

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters
por: Nies, Anne T., et al.
Publicado: (2021)

Developing nutritional component chrysin as a therapeutic agent: Bioavailability and pharmacokinetics consideration, and ADME mechanisms
por: Gao, Song, et al.
Publicado: (2021)

In Vivo Pharmacodynamics of Calophyllum soulattri as Antiobesity with In Silico Molecular Docking and ADME/Pharmacokinetic Prediction Studies
por: Fajriaty, Inarah, et al.
Publicado: (2023)

Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
por: Hu, Wen-juan, et al.
Publicado: (2020)

Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat
por: Du, Ping, et al.
Publicado: (2021)

ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients
por: Patil, Anand, et al.
Publicado: (2021)

Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs
por: Schooley, Robert T., et al.
Publicado: (2021)

Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs
por: Schooley, Robert T., et al.
Publicado: (2021)

FAF-Drugs: free ADME/tox filtering of compound collections
por: Miteva, Maria A., et al.
Publicado: (2006)

Remdesivir and Its Combination With Repurposed Drugs as COVID-19 Therapeutics
por: Chatterjee, Bhaswati, et al.
Publicado: (2022)

New potential interaction with emergency COVID-19 medicine remdesivir
Publicado: (2020)

Austalide derivative from marine-derived Aspergillus sp. and evaluation of its cytotoxic and ADME/TOPKAT properties
por: Elnaggar, Mohamed S., et al.
Publicado: (2023)

Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine
por: Manda, Vamshi K., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4c4rla25oo4kldujvlgnmcd8oe