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Single-Agent and Fixed-Dose Combination HIV-1 Protease Inhibitor Drugs in Fission Yeast (Schizosaccharomyces pombe)

Successful combination antiretroviral therapies (cART) eliminate active replicating HIV-1, slow down disease progression, and prolong lives. However, cART effectiveness could be compromised by the emergence of viral multidrug resistance, suggesting the need for new drug discoveries. The objective of...

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Detalles Bibliográficos
Autores principales: Zhang, Jiantao, Vernon, Kasey, Li, Qi, Benko, Zsigmond, Amoroso, Anthony, Nasr, Mohamed, Zhao, Richard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308830/
https://www.ncbi.nlm.nih.gov/pubmed/34202872
http://dx.doi.org/10.3390/pathogens10070804

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