Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells

Inhibition of protein–DNA interactions represents an attractive strategy to modulate essential cellular functions. We reported the synthesis of unique oligoamide-based foldamers that adopt single helical conformations and mimic the negatively charged phosphate moieties of B-DNA. These mimics alter t...

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Detalles Bibliográficos
Autores principales: Corvaglia, Valentina, Ait Mohamed Amar, Imène, Garambois, Véronique, Letast, Stéphanie, Garcin, Aurélie, Gongora, Céline, Del Rio, Maguy, Denevault-Sabourin, Caroline, Joubert, Nicolas, Huc, Ivan, Pourquier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308903/
https://www.ncbi.nlm.nih.gov/pubmed/34203395
http://dx.doi.org/10.3390/ph14070624

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