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Long-Term Oral Treatment with Non-Hypoglycemic Dose of Glibenclamide Reduces Diabetic Retinopathy Damage in the Goto-KakizakiRat Model
Diabetic retinopathy (DR) remains a major cause of vision loss, due to macular edema, retinal ischemia and death of retinal neurons. We previously demonstrated that acute administration of glibenclamide into the vitreous, or given orally at a non-hypoglycemic dose, protected the structure and the fu...
Autores principales: | Berdugo, Marianne, Delaunay, Kimberley, Lebon, Cécile, Naud, Marie-Christine, Radet, Lolita, Zennaro, Léa, Picard, Emilie, Daruich, Alejandra, Beltrand, Jacques, Kermorvant-Duchemin, Elsa, Polak, Michel, Crisanti, Patricia, Behar-Cohen, Francine F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308933/ https://www.ncbi.nlm.nih.gov/pubmed/34371786 http://dx.doi.org/10.3390/pharmaceutics13071095 |
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